STRIDE was a NIDA-sponsored randomized controlled trial that took place in Washington, DC as a collaboration with the Yale School of Medicine and Howard University Hospital. STRIDE tested the use of buprenorphine (Suboxone) vs. placebo among individuals living with HIV/AIDS and opiate use disorder.

Key Staff:

• PIs: Dr. Faye Taxman, Dr. Frederick Altice (Yale School of Medicine), Dr. William Lawson (Howard University)
• Project Managers: Amy Murphy and Marissa Kiss

Funding Source: National Institute on Drug Abuse R01DA030768

Study Location(s): Washington, DC

Major Goals: Identify the impact of the use of buprenorphine vs. placebo among individuals living with HIV/AIDS and opiate use disorder. Outcomes of interest included viral loads, physical health, decreased use of opioids, decreased criminal justice involvement.

Publications:

Delaney JA, Nance RM, Whitney BM, Altice FL, Dong X, Perez Trejo ME, Matsuzaki M, Taxman FS, Chander G, Kuo I, Fredericksen R, Strand LN, Eron JJ, Geng E, Kitahata MM, Mathews WC, Mayer K, Moore RD, Saag MS, Springer S, Chandler R, Kahana S, Crane HM. (2018). Reduced use of illicit substances, even without abstinence, is associated with improved depressive symptoms among people living with HIV. J Acquir Immune Defic Syndr 2018 Jul 19. doi: 10.1097/QAI.0000000000001803.

Nance, R.M, Trejo, M.E.P, Whitney, B.M., Delaney, J.A., Altice, F. Beckwith, C.G., Chander, G., Chandler, R., Christopoulous, K, Cunningham, C., Cunningham, W.E., Rio, C.D., Donovan, D., Eron, J.J., Frederkcson, R.J., Eron, J.J., Fredericksen, R.J., Kahana, S., Kitahata, M.M., Kronmal, R., Kuo, I. Kurth, A., Mathews, C., Mayer, K.H., Moore, R.D., Mugavero, M.J., Quellet, L.J., Quan, V.M., Saag, M. S., Simoni, J.M. Springer, S., Strand, L. Taxman, F.S., Young, J.D., & Crane, H.M. (accepted). Impact of abstinence and of reducing illicit drug use without abstinence on HIV viral load, Critical Infectious Diseases.

Loeliger KB, Biggs ML, Young R, Seal DW, Beckwith CG, Kuo I, et al. (2017). Gender differences in HIV risk behaviors among persons involved in the U.S. criminal justice system and living with HIV or at risk for HIV: a "seek, test, treat, and retain" harmonization consortium. AIDS and Behavior. doi:10.1007/s10461-017-1722-9.

Wooditch, A., Mbaba, M., Kiss, M., Lawson, W., Taxman, F., Altice, FL. (2018). Housing Experiences among Opioid-Dependent, Criminal Justice-Involved Individuals in Washington, DC. Journal of Urban Health 95 (1), 61-70.

Mbaba, M., Brown, S., Wooditch, A., Kiss, M., Murphy, A., Kumari, S., Altice, F., Lawson, W., & Springer, S. (2018). Prevalence, Diagnosis, and Treatment Rates of Mood Disorders among Opioid Users under Criminal Justice Supervision. Substance Use and Misuse, 54:1-10.

Key Presentations:

“Residential Mobility and Housing Instability among Justice-involved African-American Opioid Abusers.” Presented with Alese Wooditch and Faye S. Taxman at the College on Problems of Drug Dependence Annual Meeting, San Juan, Puerto Rico, June 16, 2014.

“Predicting Compliance with Medication Regimens among Justice-involved Opioid Users.” Presented with Alese Wooditch and Faye S. Taxman at the American Society of Criminology Annual Meeting, Atlanta, GA, November 20, 2013.

“Risk Behaviors Associated with HIV, HBV, and HCV Infection among Opioid-dependent Individuals under Criminal Justice Supervision.” Presented with Mary Mbaba, Suneeta Kumari, Alese Wooditch, Faye S. Taxman, William Lawson, and Frederick Altice at the American Public Health Association Annual Meeting, Boston, MA, November 5, 2013.

 “Mood Disorders in Opioid Abusers under Criminal Justice Supervision.” Presented with William Lawson, Alese Wooditch, Faye S. Taxman, Suneeta Kumari, Tanya Alim, and Frederick Altice at the American Psychiatric Association annual meeting, San Francisco, CA, May 19, 2013.

“Addressing Health Disparities among Minority Populations by Assessing HIV Stigma among Opioid-Dependent Individuals under Community Supervision.” Presented with Mary Mbaba, Suneeta Kumari, Alese Wooditch, Sandra Wise, William Lawson, Faye S. Taxman, and Frederick Altice at the Health Disparities Research Conference, Washington, DC, April 25, 2013.

“HIV Stigma among Opioid-Dependent Individuals under Criminal Supervision.” Poster presented with Mary Mbaba, Suneeta Kumari, Alese Wooditch, Sandra Wise, William Lawson, Faye S. Taxman, and Frederick Altice at the International Conference on Stigma, Washington, DC, November 30, 2012.

“Health Conditions among Opioid-Dependent Individuals under Community Supervision.” Presented with Alese Wooditch, Sandra Wise, William Lawson, Faye S. Taxman, and Frederick Altice at the American Society of Criminology’s Annual Meeting, Chicago, IL, November 13-17, 2012.